2019 年第 4 期 第 14 卷

血络康汤液足浴治疗寒凝血瘀型糖尿病周围神经病变的临床效果

Clinical effect of Xueluokang decoction lavipeditum on diabetic peripheral neuropathy of cold-stagnation and blood-stasis type

作者：李伯武孙光荣贺仲晨李军康立华谭方王一佼陈弘东李雪莉

英文作者：

单位：100013北京市和平里医院内分泌科（李伯武、贺仲晨、李军、康立华、谭方、王一佼、陈弘东、李雪莉），内分泌科与“3+3薪火传承工作室”（孙光荣）

英文单位：

关键词：糖尿病周围神经病变；血络康汤液；中医外治疗法；震动感觉阈值

英文关键词：

• 摘要：

• 【摘要】目的    评价血络康汤液足浴治疗寒凝血瘀型糖尿病周围神经病变（DPN）的临床效果。方法    选取2017年1月至2018年1月在北京市和平里医院住院治疗的DPN患者70例。采用随机数字表法分为对照组和观察组，各35例。2组均采用饮食、运动指导、降糖药物、甲钴胺片等基础治疗，在此基础上，对照组予温水足浴，观察组予血络康汤液足浴，均为1次/d。治疗4周后，观察并比较2组的总体疗效、多伦多临床评分系统（TCSS）评分、震动感觉阈值（VPT）的改善情况及不良反应发生情况。结果    观察组总有效率明显高于对照组［85.7%（30/35）比60.0%（21/35）］，差异有统计学意义（P<0.05）。治疗后2组 TCSS评分、双侧下肢VPT均较治疗前降低，且观察组低于对照组［（3.2±0.8）分比（6.2±0.6）分，左侧VPT：（14.1±1.9）V比（18.2±2.1）V，右侧VPT：（13.5±1.5）V比（18.0±1.6）V］（均P<0.05）。2组不良反应发生率差异无统计学意义（P>0.05）。结论    血络康汤液足浴可以改善DPN患者临床症状、改善TCSS评分及VPT。

• 【Abstract】Objective    To evaluate the clinical effect of Xueluokang decoction lavipeditum on diabetic peripheral neuropathy(DPN) of cold-stagnation and blood-stasis type. Methods    From January 2017 to January 2018, 70 DPN patients in Beijing Hepingli Hospital were randomly divided into observation group and control group, with 35 cases in each group. Both groups were treated by rational diet, exercise guidance, hypoglycemic drugs and mecobalamin tablets. The control group was given lavipeditum with warm water and the observation group had lavipeditum with Xueluokang decoction once daily for 4 weeks. Total curative effect, score of Toronto Clinical Scoring System(TCSS), vibration perception threshold(VPT) were assessed and adverse reactions were observed. Results    Total effective rate in observation group was significantly higher than that in control group［85.7%（30/35） vs 60.0%（21/35）］(P<0.05). After treatment, TCSS score and VPT of bilateral lower limbs were lower than those before treatment and they were lower in observation group than those in control group［（3.2±0.8） vs （6.2±0.6）, left VPT: （14.1±1.9）V vs （18.2±2.1）V, right VPT: （13.5±1.5）V vs （18.0±1.6）V］(all P<0.05). There was no significant difference of the incidence of adverse reactions between groups(P>0.05). Conclusion    Xueluokang decoction lavipeditum can alleviate clinical symptoms, improve TCSS score and VPT in DPN patients.