2022 年第 4 期 第 17 卷

慢性阻塞性肺疾病影像学表型与冠心病关系的研究进展

Research progress of the relationship between imaging phenotype of chronic obstructive pulmonary disease and coronary atherosclerotic heart disease

作者：李杰1黄克武2

英文作者：Li Jie1 Huang Kewu2

单位：1首都医科大学附属北京安贞医院呼吸与危重症医学科,北京100029;2首都医科大学附属北京朝阳医院呼吸与危重症医学科,北京100020

英文单位：1Department of Respiratory and Critical Care Medicine Beijing Anzhen Hospital Capital Medical University Beijing 100029 China; 2Department of Respiratory and Critical Care Medicine Beijing Chao-yang Hospital Capital Medical University Beijing 100020 China

关键词：慢性阻塞性肺疾病；冠心病（冠状动脉粥样硬化性心脏病）；肺气肿表型

英文关键词：Chronicobstructivepulmonarydisease；Coronaryatheroscleroticheartdisease；Emphysemaphenotype

• 摘要：

• 慢性阻塞性肺疾病（COPD）是一种可预防和治疗的呼吸系统疾病，以气流受限不完全可逆、进行性发展为特征，高分辨率CT能够定量显示早期的肺气肿并进行分级，且能先于肺功能检查发现肺部解剖结构异常。冠心病（冠状动脉粥样硬化性心脏病）是发病率较高的慢性疾病之一，COPD影像学表型可能会增加冠心病的发病风险。本文对COPD影像学表型与冠心病关系的研究进展进行综述，以期为COPD合并冠心病的早期筛查、减少误诊和漏诊提供帮助。

• Chronic obstructive pulmonary disease (COPD) is a preventable and curable respiratory disease, which is characterized by incomplete reversibility and progressive development of airflow restriction. High resolution CT can quantitatively display and grade early emphysema, and it can detect abnormal lung anatomy before pulmonary function examination. Coronary atherosclerotic heart disease is one of the chronic diseases with high incidence rate. COPD imaging phenotype may increase the risk of coronary atherosclerotic heart disease. This article reviews the research progress of the relationship between COPD imaging phenotype and coronary atherosclerotic heart disease, in order to provide help for early screening of COPD complicated with coronary atherosclerotic heart disease and to reduce misdiagnosis and missed diagnosis.