2023 年第 2 期 第 18 卷

肥胖或超重人群中鼾症与动脉硬化的关系

The relationship between snoring and arteriosclerosis in obese or overweight people

作者：李芮张永亮

英文作者：Li Rui Zhang Yongliang

单位：中国科学技术大学附属第一医院（安徽省立医院）健康管理中心，合肥230031

英文单位：The Health Management Center the First Affiliated Hospital of University of Science and Technology of China Anhui Provincial Hospital Hefei 230031 China

关键词：鼾症；动脉硬化；肥胖；超重

英文关键词：Snoring;Arteriosclerosis;Obesity;Overweight

• 摘要：

• 目的 分析肥胖或超重人群中鼾症与动脉硬化的关系。方法 选取中国科学技术大学附属第一医院健康管理中心2019年8月至2022年3月163例肥胖或超重的受检者作为研究对象。其中不合并鼾症者80例作为非鼾症组、合并鼾症者83例作为鼾症组。记录所有受试者的年龄、体重指数及是否存在血压升高、空腹血糖或糖化血红蛋白升高、总胆固醇或低密度脂蛋白胆固醇升高等一般情况。通过检测肱踝脉搏波传导速度（baPWV）和踝肱指数判定动脉硬化结果，比较2组受试者的baPWV和踝肱指数。结果 2组受试者年龄、体重指数及血压升高、空腹血糖或糖化血红蛋白升高、总胆固醇或低密度脂蛋白胆固醇升高比例差异均无统计学意义（均P>0.05）。鼾症组的左侧和右侧baPWV均显著高于非鼾症组，左侧踝肱指数显著低于非鼾症组，差异均有统计学意义［（1 580±312）cm/s比（1 312±171）cm/s、（1 606±330）cm/s比（1 327±180）cm/s、（1.11±0.09）比（1.15±0.07）］（均P<0.05）。结论 在肥胖或超重人群中，鼾症患者更容易发生动脉硬化，所以肥胖或超重的鼾症患者发生心血管疾病的风险增加。

• Objective To analyze the relationship between snoring and arteriosclerosis in obese or overweight people. Methods  A total of 163 obese or overweight subjects were selected in the Health Management Center, the First Affiliated Hospital of University of Science and Technology of China from August 2019 to March 2022. Among them, 80 subjects without snoring were called the non-snoring group, and 83 subjects with snoring were called the snoring group. The age, body mass index, the elevation of blood pressure, fasting plasma glucose or glycosylated hemoglobin, total cholesterol or low-density lipoprotein cholesterol of all subjects were recorded. The results of arteriosclerosis were determined by measuring brachial-ankle pulse wave velocity(baPWV) and ankle-brachial index, and the baPWV and ankle-brachial index were compared between the two groups. Results  There were no significant differences in age, body mass index, rates of elevated blood pressure, fasting plasma glucose or glycosylated hemoglobin, total cholesterol or low-density lipoprotein cholesterol between the two groups(all P>0.05). The left and right baPWV of the snoring group were significantly higher than those of the non-snoring group, and the left ankle-brachial index was significantly lower than that of the non-snoring group［(1 580±312)cm/s vs (1 312±171)cm/s, (1 606±330)cm/s vs (1 327±180)cm/s, (1.11±0.09) vs (1.15±0.07)］(all P<0.05). Conclusion  In obese or overweight people, snoring patients are more likely to develop arteriosclerosis, so snoring patients with obese or overweight have an increased risk of cardiovascular diseases.