2019 年第 12 期 第 14 卷

综合评估模式联合个性化诊疗方案在老年肌少症中的应用效果

Application of comprehensive evaluation mode combined with individualized diagnosis and treatment scheme in elderly patients with sarcopenia

作者：殷琪何扬利吴晓华吴若辉李季芳康延海

英文作者：

单位：570311海口，海南省人民医院保健中心一区

英文单位：

关键词：老年肌少症；综合评估模式；个性化诊疗方案

英文关键词：

• 摘要：

• 【摘要】目的    观察综合评估模式联合个性化诊疗方案在老年肌少症中的应用效果。方法    选取2017年5月至2018年12月在海南省人民医院就诊的老年肌少症患者100例作为研究对象。采用随机数字表法分为观察组和对照组，每组50例。对照组患者按照标准评估及诊疗方案执行，观察组患者采用综合评估模式联合个性化诊疗方案。3个月后观察分析2组患者治疗进展情况及生活质量。结果    2组患者年龄、身高、体质量及病程差异均无统计学意义（均P>0.05）。治疗后2组肌肉质量、肌肉力量、肌肉功能均高于治疗前，且观察组高于对照组［肌肉质量男（7.32±0.23）kg/m2比（6.12±0.11）kg/m2、女（5.38±0.13）kg/m2比（4.02±0.45）kg/m2，肌肉力量男（29.0±3.3）kg比（26.0±1.3）kg、女（19.3±3.0）kg比（16.8±3.0）kg，肌肉功能（1.21±1.12）m/s比（0.91±0.12）m/s］，差异均有统计学意义(均P<0.05)。观察组诊疗满意度高于对照组［94.0%（47/50）比82.0%（41/50）］，差异有统计学意义（χ2=4.38，P=0.03）。观察组患者在身体状况、心理健康及社会能力方面评分均高于对照组［（33.2±2.4）分比（22.3±3.2）分、（24.2±1.3）分比（17.2±4.4）分、（23.2±4.2）分比（16.2±5.4）分］，差异均有统计学意义(t=5.23、6.08、5.18，均P<0.01)。结论    采用综合评估模式联合个性化诊疗方案能够有效提高老年肌少症的控制效果，提高患者的生活质量，提高患者健康状态。

• 【Abstract】Objective    To observe the application effect of comprehensive evaluation mode combined with individualized diagnosis and treatment scheme on elderly patients with sarcopenia. Methods    From May 2017 to December 2018, 100 elderly patients with sarcopenia were enrolled at Hainan General Hospital. The patients were randomly divided into observation group and control group, with 50 patients in each group. The control group was treated with standard diagnosis and treatment plans. The observation group was treated with comprehensive evaluation mode combined with personalized diagnosis and treatment plans. Disease progression and quality of life were analyzed. Results    There were no significant differences in age, height, weight and course of disease between groups(all P>0.05). After treatment, muscle mass, strength and function were improved and the indexes in observation group were significantly higher than those in control group［muscle mass: male（7.32±0.23）kg/m2 vs （6.12±0.11）kg/m2， female（5.38±0.13）kg/m2 vs （4.02±0.45）kg/m2; muscle strength: male（29.0±3.3）kg vs （26.0±1.3）kg, female（19.3±3.0）kg vs （16.8±3.0）kg; muscle function（1.21±1.12）m/s vs （0.91±0.12）m/s］(all P<0.05). Patient satisfaction in observation group was significantly higher than that in control group［94.0%(47/50) vs 82.0%(41/50)］(χ2=4.38, P=0.03). Scores of physical condition, mental health and social ability in observation group were significantly higher than those in control group［（33.2±2.4） vs （22.3±3.2）, （24.2±1.3） vs （17.2±4.4）, （23.2±4.2） vs （16.2±5.4）］(t=5.23, 6.08, 5.18; all P<0.01). Conclusion    Comprehensive evaluation mode combined with individualized diagnosis and treatment scheme can effectively improve the therapeutic effect on elderly patients with sarcopenia, improve the quality of life and health status.