2020 年第 8 期 第 15 卷

两种血管闭合装置在经皮冠状动脉介入治疗中的临床应用效果评价

Clinical evaluation of two vascular closure devices in percutaneous coronary intervention

作者：张新勇王成钢甄雷师树田赵雪东

英文作者：Zhang Xinyong Wang Chenggang Zhen Lei Shi Shutian Zhao Xuedong

单位：首都医科大学附属北京安贞医院急诊危重症中心北京市心肺血管病研究所100029

英文单位：Institute of Heart Lung and Blood Vessel Diseases Beijing 100029 China

关键词：经皮冠状动脉介入；ExoSeal封堵器；Perclose血管缝合器

英文关键词：Percutaneouscoronaryintervention；ExoSealvascularclosuredevice；Perclosevascularsuturedevice

• 摘要：

• 目的 评价两种血管闭合装置ExoSeal血管封堵器与Perclose血管缝合器在经皮冠状动脉介入治疗中应用的效果和安全性。方法 收集2018年1—6月首都医科大学附属北京安贞医院收治的122例经股动脉行冠状动脉介入治疗患者的临床资料。诊疗术中分别采用ExoSeal血管封堵器（ExoSeal组，58例）和Perclose血管缝合器（Perclose组，64例）方法 对股动脉穿刺点止血。记录并比较2组患者封堵成功率、操作时间、止血时间、制动时间、外周血管并发症。结果 2组患者封堵成功率和制动时间比较，差异均无统计学意义（均P＞0.05）。ExoSeal组操作时间和止血时间均明显短于Perclose组［（2.33±0.18）min比（4.15±0.40）min、（4.36±0.27）min比（6.91±0.43）min］，差异均有统计学意义（均P＜0.01）。2组外周血管并发症发生率比较，差异无统计学意义（P＞0.05）。结论 两种血管闭合装置止血用于冠状动脉介入诊治术后，并发症少，安全有效，其中Exoseal血管封堵器的操作更加简便。

• Objective To evaluate the safety and efficacy of ExoSeal vascular closure and Perclose vascular suture device in percutaneous coronary intervention(PCI). Methods From January to June 2018 clinical data of 122 patients undergoing coronary intervention through the femoral artery admitted to Beijing Anzhen Hospital, Capital Medical University were collected. ExoSeal blood vessel occluder (ExoSeal group, 58 cases) and Perclose blood vessel suture (Perclose group, 64 cases) were used. The success rate of occlusion, operation time, hemostasis time, braking time and peripheral vascular complications were compared between the two groups. Results There were no significant differences in occlusion success rate and braking time between the two groups (both P＞0.05). The operation time and hemostasis time in ExoSeal group were significantly shorter than those in Perclose group［（2.33±0.18）min vs （4.15±0.40）min,（4.36±0.27）min vs （6.91±0.43）min，both P＜0.01］. There was no significant difference in the incidence of peripheral vascular complications between the two groups (P＞0.05). Conclusion The use of ExoSeal vascular closure and Perclose vascular suture device have good effects and safety in patients undergoing PCI.