2021 年第 5 期 第 16 卷

替罗非班在急性脑梗死中应用的研究进展

Research progress of tirofiban in acute cerebral infarction

作者：田雨胡晓

英文作者：Tian Yu Hu Xiao

单位：遵义医科大学研究生院563003

英文单位：Graduate School Zunyi Medical University Guizhou Province Zunyi 563003 China

关键词：急性脑梗死；替罗非班；静脉溶栓；血管内治疗

英文关键词：Acutecerebralinfarction;Tirofiban;Intravenousthrombolysis;Endovasculartreatment

• 摘要：

• 急性脑梗死是指因脑局部缺血缺氧所导致的神经功能障碍性疾病，抗血小板治疗在急性脑梗死的治疗和二级预防中应用已达成共识。新型抗血小板聚集药物血小板糖蛋白Ⅱb/Ⅲa受体拮抗剂如替罗非班在心血管疾病应用中的安全性及有效性已得到大量临床研究认可。但对于替罗非班在急性脑梗死的应用仍存在争议，现将替罗非班在急性脑梗死中的应用进展进行综述。

• Acute cerebral infarction refers to the neurological dysfunction disease caused by cerebral ischemia and hypoxia. The application of antiplatelet therapy in the treatment and secondary prevention of acute cerebral infarction has became a consensus. The safety and efficacy of platelet glycoprotein Ⅱb/Ⅲa receptor antagonists such as tirofiban in the application of cardiovascular diseases have been recognized by a large number of clinical researches. However, the application of tirofiban in acute cerebral infarction is still controversial. This paper reviews the application progress of tirofiban in acute cerebral infarction.