2023 年第 5 期 第 18 卷

肺炎支原体感染与儿童过敏性紫癜及紫癜性肾炎关系的研究进展

Research progress on the relationship of Mycoplasma pneumoniae infection to henoch-schonlein purpura and henoch-schonlein purpura nephritis in children

作者：曹永丽1焦琼杰2祝静2赵家敏1丁霞2倪倩2黄莉3

英文作者：Cao Yongli1 Jiao Qiongjie2 Zhu Jing2 Zhao Jiamin1 Ding Xia2 Ni Qian2 Huang Li3

单位：1兰州大学第二临床医学院，兰州730000；2兰州大学第二医院小儿呼吸科，兰州730000;3兰州大学第二医院小儿肾病科，兰州730000

英文单位：1The Second Clinical Medical School Lanzhou University Lanzhou 730000 China; 2Department of Pediatric Respiratory Medicine Lanzhou University Second Hospital Lanzhou 730000 China; 3Department of Pediatric Nephrology Lanzhou University Second Hospital Lanzhou 730000 China

关键词：过敏性紫癜；紫癜性肾炎；肺炎支原体；儿童

英文关键词：Henoch-schonleinpurpura;Henoch-schonleinpurpuranephritis;Mycoplasmapneumoniae;Children

• 摘要：

• 过敏性紫癜是一种以感染为主要诱因的全身性小血管炎。过敏性紫癜肾损伤又称紫癜性肾炎，是过敏性紫癜最严重的长期并发症。诸多研究发现肺炎支原体感染是导致过敏性紫癜发病的重要因素之一，并可促进和加重紫癜性肾炎的发生和发展。现就肺炎支原体所致过敏性紫癜、紫癜性肾炎的临床表现及可能作用机制进行阐述，以期更好地了解其发生发展规律，为临床治疗提供新的思路。

• Henoch-schonlein purpura(HSP) is a systemic small vasculitis with infection as the main inducement. HSP kidney injury, also known as HSP nephritis(HSPN), is the most serious long-term complication of HSP. Many studies have found that Mycoplasma pneumoniae infection is one of the important factors leading to the pathogenesis of HSP, and can promote and aggravate the occurrence and development of HSPN. Now the clinical manifestations and possible mechanisms of HSP and HSPN caused by Mycoplasma pneumoniae are elaborated, in order to better understand their laws of occurrence and development and provide new ideas for clinical treatment.