2024 年第 2 期 第 19 卷

黄芪和鬼箭羽对药治疗糖尿病周围神经病变临床经验探析

Clinical experience Astragalus and Gymnema sylvestre in the treatment of diabetic peripheral neuropathy

作者：李伯武1,2黄举凯1赵琦瑶1李皎月1张晔1胡超越1贺仲晨2杨晓晖1

英文作者：Li Bowu12 Huang Jukai1 Zhao Qiyao1 Li Jiaoyue1 Zhang Ye1 Hu Chaoyue1 He Zhongchen2 Yang Xiaohui1

单位：1北京中医药大学东直门医院，北京100700；2北京市和平里医院内分泌科，北京100013

英文单位：1Dongzhimen Hospital Beijing University of Chinese Medicine Beijing 100700 China; 2Department of Endocrinology Beijing Hepingli Hospital Beijing 100013 China

关键词：黄芪；鬼箭羽；对药；糖尿病周围神经病变；三同理论

英文关键词：Astragalus;Gymnemasylvestre;Herbpair;Diabeticperipheralneuropathy;Threesimultaneoustheory

• 摘要：

• 黄芪、鬼箭羽是杨晓晖教授治疗糖尿病周围神经病变（DPN）的常用对药。本文通过对古代中医文献及现代药理研究的梳理，探讨黄芪、鬼箭羽对药治疗DPN的配伍特点和临床应用，认为二者具有气血同调、表里同治、寒温同用的功效，契合DPN“麻是气虚，木是痰湿死血”“微型癥瘕”的病机特点，是杨晓晖教授“三同理论”防治糖尿病并发症的具体体现，临床效果显著，值得进一步探索研究。

• Astragalus and Gymnema sylvestre are commonly used pair of herbs in Professor Yang Xiaohui′s treatment of diabetic peripheral neuropathy (DPN). Integrating ancient Chinese medicine literature and modern pharmacological research, this paper discusses the compatibility characteristics and clinical application of Astragalus and Gymnema sylvestre in the treatment of DPN. It is believed that they have the effects of regulating qi and blood, treating the exterior and interior, and being applicable in both cold and warm conditions. This aligns with the pathogenesis characteristics of DPN, "numbness is qi deficiency, hypoesthesia is phlegm-damp blocking blood" and "micro-mass lesions". It is the specific embodiment of Professor Yang Xiaohui′s "Three simultaneous theory" in preventing and treating diabetic complications. Astragalus and Gymnema sylvestre herb pair improves clinical efficacy significantly, and worth further exploration and research.