2024 年第 12 期 第 0 卷

骨类器官在骨关节炎疾病中的运用与展望

Application and prospect of bone organoids in osteoarthritis disease

作者：张志杰1黄晖1李科1王波1周塏2

英文作者：Zhang Zhijie1 Huang Hui1 Li Ke1 Wang Bo1 Zhou Kai2

单位：1海南医科大学附属海南医院(海南省人民医院)运动医学科，海口570311；2海南医科大学第二附属医院手足显微外科，海口570311

英文单位：1Department of Sports Medicine Affiliated Hainan Hospital of Hainan Medical University Hainan General Hospital Haikou 570311 China; 2Hand and Foot Microsurgery the Second Affiliated Hospital of Hainan Medical University Haikou 570311 China

关键词：骨关节炎；骨类器官；组织工程；再生医学

英文关键词：  Osteoarthritis;Boneorganoids;Tissueengineering;Regenerativemedicine

• 摘要：

• 本文综述了骨类器官在骨关节炎疾病中的应用情况，并对未来发展趋势进行了展望。首先对骨关节炎的定义、治疗现状及挑战进行了梳理，全面了解该疾病的背景和重要性。随后阐述了骨类器官的定义以及骨类器官的概念与特征，并对骨类器官在骨关节炎疾病领域的研究进展进行了详细介绍。最后分析了骨类器官在骨关节炎治疗中的潜在价值和未来的发展趋势，以期为相关研究和实践提供参考。

• This article reviews the application of bone organoids in osteoarthritis diseases, and prospects the future development trend. Firstly, the definition, treatment status and challenges of osteoarthritis are sorted out to fully understand the background and importance of this disease. Then, the definition, concept and characteristics of bone organoids are described, and the research progress of bone organoids in the field of osteoarthritis was introduced in detail. Finally, the potential value and future development trend of bone organoids in the treatment of osteoarthritis are analyzed, in order to provide reference for related research and practice.