2025 年第 5 期 第 20 卷

健脾温阳方治疗基层参训人员脾胃虚弱型上腹疼痛综合征的临床研究

Clinical study of Jianpi Wenyang decoction in the treatment of epigastric pain syndrome of spleen and stomach weakness in grassroots training participants

作者：崔艺馨1王德财2谢东晴3王海明1张印1王雨佳1李绍旦1

英文作者：Cui Yixin1 Wang Decai2 Xie Dongqing3 Wang Haiming1 Zhang Yin1 Wang Yujia1 Li Shaodan1

单位：1中国人民解放军总医院第六医学中心中医医学部，北京100853；2航天中心医院第二门诊部，北京100049；3中国人民解放军总医院第一医学中心超声科，北京100039

英文单位：1Department of Traditional Chinese Medicine the Sixth Medical Center of Chinese PLA General Hospital Beijing 100853 China; 2The Second Department of Outpatient Aerospace Center Hospital Beijing 100049 China; 3Department of Ultrasound the First Medical Center of Chinese PLA General Hospital Beijing 100039 China

关键词：上腹疼痛综合征；健脾温阳方；消化不良；脐疗

英文关键词：Epigastricpainsyndrome;JianpiWenyangdecoction;Dyspepsia;Navel-therapy

• 摘要：

• 目的 探讨健脾温阳方治疗基层参训人员脾胃虚弱型上腹疼痛综合征（EPS）的临床效果。方法 选取2023年2—8月中国人民解放军总医院第一医学中心收治的84例脾胃虚弱型功能性消化不良患者作为研究对象，按照随机数字表法分为对照组（42例）和观察组（42例）。对照组在基础治疗基础上给予奥美拉唑镁肠溶片治疗，观察组在基础治疗基础上给予健脾温阳方外敷治疗。比较2组患者的胃肠症状评分、胃运动功能、中医证候积分、疗效、安全性。结果 试验期间对照组脱落2例。治疗后，2组胃肠道症状评分均低于治疗前，且观察组餐后饱胀、早饱感方面的评分均低于对照组，差异均有统计学意义(均P＜0.05)。治疗后，2组患者胃窦收缩幅度、胃窦收缩频率、胃窦运动指数均高于治疗前，且观察组胃窦运动指数高于对照组，差异均有统计学意义(均P＜0.05)。治疗后，2组患者中医证候积分均低于治疗前，且观察组纳差、乏力、进食后加重的中医证候积分均低于对照组，差异均有统计学意义(均P＜0.05)。观察组治疗总有效率高于对照组［95.2%（40/42）比72.5%（29/40）］，差异有统计学意义(χ2=7.940，P=0.005)。治疗期间，2组患者均未发生不良反应。结论 健脾温阳方不仅明显改善腹部胀满、早饱感等EPS的临床症状，还能缓解乏力、纳差等伴随症状，从而提高参训人员的生活质量。

• Objective To investigate the clinical effect of Jianpi Wenyang decoction in the treatment of epigastric pain syndrome (EPS) of spleen and stomach weakness in grassroots training participants. Methods A total of 84 patients with functional dyspepsia of spleen and stomach weakness admitted to the First Medical Center of Chinese PLA General Hospital from February to August 2023 were selected as the research objects. According to the random number table method, they were divided into the control group (42 cases) and the observation group (42 cases). The control group was treated with omeprazole magnesium enteric-coated tablets on the basis of basic treatment, and the observation group was treated with external application of Jianpi Wenyang decoction on the basis of basic treatment. The gastrointestinal symptom scores, gastric motor function, traditional Chinese medicine syndrome scores, efficacy and safety were compared between the two groups. Results During the experiment, 2 cases of control group dropout occurred. After treatment, the gastrointestinal symptom scores of the two groups were significantly lower than those before treatment, and the scores of postprandial fullness and early satietythe in the observation group were lower than those in the control group (all P<0.05). After treatment, the antral contraction amplitude, antral contraction frequency and antral motility index of the two groups were higher than those before treatment, and the antral motility index of the observation group was higher than that of the control group (all P<0.05). After treatment, the traditional Chinese medicine syndrome scores of the two groups were lower than those before treatment, and the traditional Chinese medicine syndrome scores of poor appetite, fatigue, and aggravation after eating in the observation group were lower than those in the control group (all P<0.05). The total effective rate of the observation group was higher than that of the control group ［95.2%(40/42) vs 72.5%(29/40)(χ2=7.940, P=0.005). During the treatment, no adverse reactions occurred in the two groups. Conclusion Jianpi Wenyang decoction can not only significantly improve the clinical symptoms of EPS such as abdominal distension and early satiety, but also relieve the accompanying symptoms such as fatigue and poor appetite, so as to improve the quality of life of the training participants.