2025 年第 7 期 第 20 卷

儿童抽动障碍共患强迫障碍研究进展

Research progress of comorbid tic disorders and obsessive-compulsive disorder in children

作者：于潇璐1周荣易2谢新月1张祎1贾佳1

英文作者：Yu Xiaolu1 Zhou Rongyi2 Xie Xinyue1 Zhang Yi1 Jia Jia1

单位：1河南中医药大学儿科医学院，郑州450000；2河南中医药大学第一附属医院儿科医院，郑州450000

英文单位：1Pediatric Medical College Henan University of Chinese Medicine Zhengzhou 450000 China; 2Pediatric Hospital the First Affiliated Hospital of Henan University of Chinese Medicine Zhengzhou 450000 China

关键词：抽动障碍；强迫障碍；共患病

英文关键词：Ticdisorders;Obsessive-compulsivedisorder;Comorbidity

• 摘要：

• 抽动障碍是儿童青少年时期常见的神经精神障碍性疾病，临床上常伴有一种或多种共患病，增加了疾病诊疗的难度，成为近年来的重点关注方向。抽动障碍共患强迫障碍是临床上较常见的共患病，研究显示，抽动障碍与强迫障碍之间存在复杂的双向因果关系，共患强迫障碍增加了抽动障碍诊治的复杂性和困难度，导致临床治疗效果的降低和病程的延长，成为抽动障碍临床治疗面临的一个重大难题和难治性抽动障碍产生的重要诱因，在国际上引起广泛关注，而目前国内学术界对此关注相对较少。本文结合全球最新文献围绕抽动障碍共患强迫障碍的临床特征、病因病机研究以及临床治疗探索3个方面进行综述，旨在为抽动障碍共患病的相关研究提供参考。

• Tic disorders are common neuropsychiatric disorders in children and adolescents. They are often accompanied by one or more comorbidities, which increase the difficulty of disease diagnosis and treatment and have become the focus of attention in recent years. Tic disorders comorbid with obsessive-compulsive disorder is a common comorbidity in clinical practice. Studies have shown that there is a complex bidirectional causal relationship between tic disorders and obsessive-compulsive disorder. Comorbid obsessive-compulsive disorder increases the complexity and difficulty of diagnosis and treatment of tic disorders, resulting in reduced clinical treatment effect and prolonged course of disease. It has become a major problem in the clinical treatment of tic disorders and an important cause of refractory tic disorders. It has attracted wide attention in the world, but there is relatively little attention in domestic academic circles. This article reviews the latest global literature on the clinical characteristics, etiology, pathogenesis and clinical treatment of tic disorders comorbid with obsessive-compulsive disorder, aiming to provide a reference for related research on tic disorders comorbid with obsessive-compulsive disorder.