2020 年第 8 期 第 15 卷

改善脓毒症患者出院预后的临床研究进展

Clinical research on improving discharge prognosis of sepsis patients

作者：冯迟刘晓巍王玥

英文作者：Feng Chi Liu Xiaowei Wang Yue 

单位：首都医科大学附属北京妇产医院应急医疗分队100026

英文单位：Emergency Medical Service Team Beijing Obstetrics and Gynecology Hospital Capital Medical University Beijing 100026 China

关键词：脓毒症；预后；干预措施

英文关键词：Sepsis;Prognosis;Managementcountermeasures

• 摘要：

• 脓毒症被定义为继发于全身严重感染的急性器官功能障碍综合征，死亡率逐年下降，但研究发现脓毒症患者出院后远期预后不良，且有健康状况慢性恶化的趋势。本研究通过PubMed对脓毒症相关文章进行了检索，主要关注与脓毒症出院后生存质量相关的临床试验与大型纵向临床研究，对脓毒症患者的流行病学、病理生理学和临床后遗症进行了综述研究，并提出干预策略，以供临床参考。

• Sepsis is defined as acute organ dysfunction syndrome which is a secondary to severe systemic infection. The death rate decreased year by year, but sepsis patients can have poor long-term prognosis after discharge from hospital and there is a tendency for chronic deterioration of the health. This research retrieved the sepsis-related articles through PubMed, focusing on clinical trials and large longitudinal clinical studies related to the life quality of sepsis patients after discharge from hospital. The epidemiology, pathophysiology and clinical sequelae of sepsis patients and  intervention strategies are discussed.