2021 年第 5 期 第 16 卷

微小RNA-186在泌尿生殖系统肿瘤中的研究进展

Research progress on microRNA-186 in urogenital tumors

作者：王毓斌1李荣山2

英文作者：Wang Yubin1 Li Rongshan2

单位：1山西医科大学第二医院博士后工作站，太原030001；2山西省人民医院肾内科，太原030012

英文单位：1Postdoctoral Workstation Second Hospital of Shanxi Medical University Taiyuan 030001 China; 2Department of Nephrolog Shanxi Provincial People′s Hospital Taiyuan 030012 China

关键词：泌尿生殖系统肿瘤；微小RNA-186；肿瘤生物学

英文关键词：Urogenitaltumors;MicroRNA-186;Tumorbiology

• 摘要：

• 微小RNA（miR）参与了癌变和人类癌症的发展，关于miR-186在各种癌症包括泌尿生殖系统肿瘤中的表达已经进行了大量研究，结果均表明miR-186影响着肿瘤中的各种生物过程，可作为泌尿生殖系统肿瘤诊断和预后评估的标志物。本文就miR-186在泌尿生殖系统肿瘤中的研究进展予以综述。

• MicroRNA (miR) involves with carcinogenesis and development of cancer in human. MiR-186 has been extensively studied in various cancers including urogenital tumors. It is reported that miR-186 affects various biological processes in tumors, and may serve as a marker for the diagnosis and prognosis of urogenital tumors. This paper reviews the research progress on miR-186 in urogenital tumors.