2022 年第 5 期 第 17 卷

首夜效应在睡眠障碍相关疾病中的研究进展

Research progress of first night effect in sleep-related diseases

作者：李焕1陈琪2房芳2

英文作者：Li Huan1 Chen Qi2 Fang Fang2

单位：1北京市心肺血管疾病研究所首都医科大学附属北京安贞医院睡眠医学中心，北京100029；2首都医科大学附属北京安贞医院睡眠医学中心，北京100029

英文单位：1Beijing Institute of Heart Lung and Blood Vessel Diseases Sleep Medical Center Beijing Anzhen Hospital Capital Medical University Beijing 100029 China; 2Sleep Medical Center Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

关键词：首夜效应；睡眠障碍相关疾病；连续睡眠监测；睡眠追踪器

英文关键词：Firstnighteffect;Sleep-relateddiseases;Multi-nightsleepmonitoring;Sleeptracker

• 摘要：

• 人类进化中仍然存留因睡眠环境改变而影响睡眠的特质，在陌生环境下的第1晚睡眠过程中，大脑的活跃度及觉醒增强，影响睡眠，即首夜效应。根据目前的指南，睡眠障碍相关疾病的诊断均基于单夜监测手段，但是睡眠监测结果常常受首夜效应影响，经典单夜监测诊断睡眠障碍相关疾病准确度受到挑战，连续多夜监测成为新的关注问题。本文在介绍首夜效应的基础上，阐述其在不同人群和睡眠障碍相关疾病中的表现和影响，并分析连续睡眠监测的必要性及可行性。旨在为优化睡眠障碍相关疾病监测方案提供依据。

• The characteristics of sleep changing with different environments still exist in the human evolution process. The brain activities and arousal appear more frequently during the first night sleep in a strange place, which is regarded as first night effect (FNE). The diagnosis of sleep disorders usually relies on single-night monitoring according to current guidelines, but the results of sleep evaluation are often affected by FNE. Therefore, the accuracy of traditional methods gets impact, while multi-night sleep monitoring has arisen more attention. Based on the introduction of FNE, this paper not only elaborates the manifestations and effects of FNE on different populations and sleep-related diseases, but also analyzes the feasibility and necessity of multi-night sleep monitoring to provide an optimized monitoring scheme for the diseases.