2022 年第 3 期 第 17 卷

卷柏总黄酮研究进展

Advance in research of total flavonoids from Selaginella tamariscina

作者：张莲珠1 刘君1李驰坤2张雅剑1宋宇1成光宇2

英文作者：Zhang Lianzhu1 Liu Jun1 Li Chikun2 Zhang Yajian1 Song Yu1 Cheng Guangyu2

单位：1海南热带海洋学院水产与生命学院热带海洋生物资源利用与保护教育部重点实验室海南省热带海洋渔业资源保护与利用重点实验室，三亚572022；2长春中医药大学附属医院中医药研究中心，长春130021

英文单位： 1Key Laboratory of Utilization and Conservation for Tropical Marine Bio-resources Ministry of Education Hainan Key Laboratory for Conservation and Utilization of Tropical Marine Fishery Resources College of Fishery and Life Science Hainan Tropical Ocean University Sanya 572022 China; 2Chinese Medicine Research Center the Affiliated Hospital of Changchun University of Chinese Medicine Changchun 130021 China

关键词：卷柏总黄酮；化学成分；质量控制；药理活性

英文关键词：TotalflavonoidsfromSelaginellatamariscina;Chemicalcontituent;Qualitycontrol;Pharmacologicalactivity

• 摘要：

• 卷柏为传统中药，在临床应用广泛，其中富含黄酮类成分，具有抗氧化、抗肿瘤、降血糖、抗过敏、调血脂、改善认知障碍、抗骨质疏松及促血管生成等活性。本文对卷柏总黄酮在化学成分、提取纯化、质量控制、药理活性等方面的研究进展进行综述，为卷柏及其主要成分总黄酮的研究开发提供参考。

• As a traditional Chinese medicine, Selaginella tamariscina is widely used in clinic. It is rich in flavonoids and has good effects on antioxidant, antitumor, regulating blood glucose, antianaphylaxis, decreasing serum lipids, improving cognition, anti-osteoporotic, promoting angiogenesis and so on. This paper reviews chemical constituents, extracting and purifing method, quality control and pharmacological activity of total flavonoids from Selaginella tamariscina.